BRAINS! Achievement, Description, Unlock & Secret Number | Binding of Isaac Wiki

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Binding of Isaac Achievement: BRAINS!

Achievements

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Description	Unlocked Challenge #27.
Unlock	Defeat Isaac 5 times
In-Game Secret Number	271
Platforms	All
DLC Required	Added in Afterbirth
Achievement Description

Description: Unlocked a new item.
Unlock: Defeat Hush as Cain
In-Game Secret Number: 181

Description: Unlocked a secret.
Unlock: Donate 10 coins to the Greed Machine
In-Game Secret Number: 243

Special Hanging Shopkeepers

Description: Unlocked a new item.
Unlock: Defeat Ultra Greed as Isaac
In-Game Secret Number: 192

Description: Unlocked a new item.
Unlock: Donate 30 coins to the Greed Machine
In-Game Secret Number: 244

Description: Unlocked a new item.
Unlock: Defeat Satan as Lilith
In-Game Secret Number: 220

Description: Unlocked a new starting item.
Unlock: Donate 439 coins to the Greed Machine
In-Game Secret Number: 248

Eve now holds Razor Blade

Description: Unlocked a new co-player baby.
Unlock: Earn all hard mode completion marks as Judas
In-Game Secret Number: 263

Description: Unlocked a new starting item.
Unlock: Donate 68 coins to the Greed Machine
In-Game Secret Number: 245

Cainholds Paperclip

Description: Unlocked a new item.
Unlock: Defeat Hush as Keeper
In-Game Secret Number: 191

Keepernow holds... A Penny!

Description: Unlocked a new item.
Unlock: Complete challenge #28
In-Game Secret Number: 231

D8

Description: Unlocked a new co-player baby.
Unlock: Defeat Mega Satan as The Lost
In-Game Secret Number: 215

Description: Unlocked a new item.
Unlock: Defeat Ultra Greed as Lazarus
In-Game Secret Number: 200

Description: Unlocked a new item.
Unlock: Complete challenge #24
In-Game Secret Number: 227

Description: Unlocked a new co-player baby.
Unlock: Defeat Mega Satan as Isaac
In-Game Secret Number: 205

Description: Unlocked a new item.
Unlock: Defeat Isaac as Lilith
In-Game Secret Number: 218

Description: Unlocked a new item.
Unlock: Defeat Hush as The Lost
In-Game Secret Number: 189

Sworn Protector

Description: Unlocked a new co-player baby.
Unlock: Earn all hard mode completion marks as ???
In-Game Secret Number: 252

Description: Unlocked a new co-player baby.
Unlock: Defeat Mega Satan as Azazel
In-Game Secret Number: 212

Description: Unlocked a new item.
Unlock: Complete challenge #30 (Removed in Afterbirth+ The unlock is bugged and actually unlocks Kidney Stone)
In-Game Secret Number: 233

Description: Unlocked a new item.
Unlock: Complete challenge #22
In-Game Secret Number: 225

Get out of Jail Free Card

Description: Unlocked a new co-player baby.
Unlock: Earn all hard mode completion marks as Lilith
In-Game Secret Number: 260

Description: Unlocked Challenge #26.
Unlock: Defeat ??? or The Lamb for the 1st time, and defeat Satan as Isaac
In-Game Secret Number: 270

Description: Nerd x 1000000
Unlock: Unlock all of the secrets and endings, and collect every item in the game
In-Game Secret Number: 235

Description: Unlocked...
Unlock: Defeat Mega Satan as every character
In-Game Secret Number: 276

Description: Unlocked a new item.
Unlock: Complete the Boss Rush as Keeper
In-Game Secret Number: 240

Description: Unlocked Challenge #22.
Unlock: Defeat Mom for the 1st time
In-Game Secret Number: 266

Description: Unlocked a new item.
Unlock: Complete challenge #26
In-Game Secret Number: 229

Description: Unlocked Challenge #23.
Unlock: Destroy 10 tinted rocks and defeat Mom's Heart 11 times
In-Game Secret Number: 267

Description: Unlocked a new starting item.
Unlock: Donate 879 coins to the Greed Machine
In-Game Secret Number: 250

Lostholds Holy Mantle

Description: Unlocked Challenge #29.
Unlock: Defeat Mom for the 1st time
In-Game Secret Number: 273