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Welcome to The Binding of Isaac challenge guide. Click on a challenge to learn more.

https://bindingofisaacwiki.com/i/q/bindingofisaacwiki__challenges?b=&c=&e=&i=&h=No&d=&_n=200

	Order	Featured	Hearts (with Amounts)	Conditions	Goal	Unlocks
Pitch Black	1	Isaac	3 Red Hearts	Curse of Darkness, Curse of the Unknown	Mom	Rune of Hagalaz

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