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6 rooms Items

Welcome to The Binding of Isaac item guide. Click on an item to learn more.
Item ID
Clicker 482 Clicker Transforms Isaac into another random character.
Coupon 521 Coupon Upon use, makes a random item from a shop, devil deal, or black market free.
Smelter 479 Smelter Consumes Isaac's currently held trinket and applies its effect permanently.
Void 477 Void Consumes all pedestal items in the room. Active items will have their effects added to Void, and passive items will grant stat upgrades.
Book of Revelations 78 Book of Revelations Adds 1 soul heart, increases the chance for a Devilor Angel Room to appear, and increases the chance for the next boss to be a Horseman (except on XL floors and floors with fixed bosses such as Mom).
Book of Secrets 287 Book of Secrets Upon use, gives the effect of Treasure Map, The Compass, or Blue Map for the duration of the current floor.
Crystal Ball 158 Crystal Ball Reveals the map (except the Super Secret Room) and drops a random Tarot Card or soul heart.
D100 283 D100 Upon use, rerolls all passive items on Isaac like the D4, every pedestal item in the room like The D6, and every pickup like the D20.
D20 166 D20 Rerolls all pickups in the current room.
D4 284 D4 Rerolls all of Isaac's items.
Deck of Cards 85 Deck of Cards Gives Isaac a random Tarot Card.
Flush! 291 Flush! Changes all enemies in the room into poop. Does not work on all enemies (Knights and bosses are immune). Instantly kills Dingle, Dangle, and Brownie.
Head of Krampus 293 Head of Krampus Fires a cross-patterned brimstone shot, just like The Fallen and Krampus shoot.
Isaac's Tears 323 Isaac's Tears Shoots 8 tears around Isaac, which retain the damage, shot speed, and special effects of his tears. Each tear shot by Isaac increases item charge by one.
Mom's Bottle of Pills 102 Mom's Bottle of Pills Gives Isaac a random pill, and will cause him to drop any held Q-slot item (If any). The player will only receive six different pill types in one playthrough.
My Little Unicorn 77 My Little Unicorn Upon use, grants invulnerability and increased speed for five seconds, removing the ability to shoot tears and replacing it with the ability to deal contact damage to enemies.
Prayer Card 146 Prayer Card Grants an eternal heart per use.
Satanic Bible 292 Satanic Bible Upon activation, Isaac gains a black heart.
Scissors 325 Scissors Upon use, turns Isaac's head into a stationary familiar for the current room which fires normal tears that deal 3.5 damage.
The Bible 33 The Bible Upon activation, Isaac gains flight, allowing him to pass over all obstacles in the current room. Instantly kills Mom, Mom's Heart, and It Lives when activated, but will kill Isaac when activated while fighting Satan.
The D6 105 The D6 Allows Isaac to re-roll collectible items in the current room into other items, depending on the current room's Item Pool.
The Gamekid 93 The Gamekid Upon use, turns the character into a into a Pac-Man-like creature for 5 seconds, granting invulnerability, inflicting fear on all enemies, and replenishing half a red heart container for every two enemies killed.
The Nail 83 The Nail Adds one soul heart and allows the breaking of rocksand damaging enemies by simply walking over them. Increases damage and decreases speed. All effects except for the Soul Heart wear off upon leaving the room.
The Necronomicon 35 The Necronomicon Damages all enemies in the room significantly.
The Pinking Shears 107 The Pinking Shears Separates Isaac's head and body for the current room. Isaac's head, which now has flight, will be under the player's control, while his body will seek out enemies to attack by contact damage.
Undefined 324 Undefined Teleports Isaac to either the Secret Room, Super Secret Room, Treasure Room, or I AM ERROR.
We Need to Go Deeper! 84 We Need to Go Deeper! Creates a trapdoor to go to the next floor. If used in The Womb, it will create a trapdoor to Sheol, even if the player hasn't unlocked it.
White Pony 181 White Pony Passively grants flight and increased speed. Upon use, Isaac charges in the direction the pony is facing, becoming invulnerable during the charge and damaging enemies while also casting the effect of Crack the Sky.