Item: Champion Belt Share

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Item: 157.0 Bloody Lust Increases damage as Isaac receives damage. Damage increase stays for the whole floor.

Item: 15.0 <3 Grants Isaac one red heart container and fully restores Isaac's health.

Item: 262.0 Missing Page 2 Gives 1 black heart. Upon taking damage that reduces Isaac's health to one heart or less, activates The Necronomicon effect, dealing 40 damage to all enemies in the room.

Item: 301.0 Cancer Adds 3 soul hearts. Grants The Wafer effect for the current room upon taking damage.

Item: 142.0 Scapular Once per room, when Isaac is reduced to his last half red Heart, the aura around his head temporarily vanishes and he is granted one Soul Heart.

Item: 418.0 Fruit Cake Isaac's tears gain a random effect that changes every shot.

Item: 207.0 Ball of Bandages Orbiting familiar that deals damage to enemies. If collected while already having one, makes the familiar evolve. Only drops from Horsemen. Similar to Cube of Meat.

Item: 243.0 Trinity Shield Isaac gains a shield that protects him from enemy shots.

Item: 473.0 Big Chubby Spawns a familiar that slowly charges forward and damages enemies in its path.

Item: 230.0 Abaddon Increases damage and speed, removes all red heart containers, grants six black hearts, and adds a chance to shoot fear tears.

Item: 546.0 Dad's Ring Creates a ring of light around Isaac that petrifies enemies in contact.

Item: 466.0 Contagion The first enemy killed in a room explodes and poisons nearby enemies. Poisoned enemies will also explode upon death.

Item: 228.0 Mom's Perfume Adds a chance to shoot fear tears and decreases tear delay by 1.

Item: 50.0 Steven Increases Damage by 1.

Item: 99.0 Little Gish Spawns a familiar that follows Isaac around and fires slowing tears, impeding enemies' speed.

Item: 180.0 The Black Bean When taking damage, Isaac farts, causing poison damage to all enemies in range.

Item: 353.0 Bomber Boy +5 bombs. Isaac's bombs will now explode in a large cross-shaped pattern (roughly 5 bombs explosions wide). This also affects troll bombs.

Item: 11.0 1up! Gives an extra life. Upon death, you will respawn in the previous room with full health and lose the 1up!.

Item: 246.0 Blue Map Shows secret and super secret room locations on the map.

Item: 513.0 Bozo Increases damage by a flat 0.1 and grants a soul heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a rainbow poop.

Item: 461.0 Parasitoid Adds a chance to fire an egg sack which spawns slowing creep and spawns a blue fly or spider upon hitting an enemy.

Item: 535.0 Blanket Grants one soul heart. Upon entering a boss room, grants a shield that blocks one hit, then disappears.

Item: 446.0 Dead Tooth While firing, Isaac gains a green aura that poisons nearby enemies.

Item: 374.0 Holy Light Isaac has a random chance to fire a Holy tear, which, when it hits an enemy, will spawn a Crack the Sky-style light beam on the same enemy, dealing damage.

Item: 151.0 The Mulligan Tears have a 1/6 chance of spawning allied blue flies when they hit an enemy.

Item: 16.0 Raw Liver Grants 2 Heart Containers and completely restores health.

Item: 114.0 Mom's Knife Isaac's tears are replaced by a knife that pierces enemies, can travel through obstacles, and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power.

Item: 217.0 Mom's Wig Adds a chance to spawn blue spiders when firing tears. Restores 1 red heart.

Item: 277.0 Lil Haunt A familiar that damages enemies by chasing them as well as inducing the fear effect.

Item: 280.0 Sissy Longlegs Wanders about the room, occasionally spawning blue spiders.

Item: 136.0 Best Friend Deploys a decoy Isaac that eventually explodes with an increased blast radius.

Item: 207.0 Ball of Bandages Orbiting familiar that deals damage to enemies. If collected while already having one, makes the familiar evolve. Only drops from Horsemen. Similar to Cube of Meat.

Item: 28.0 The Belt Increases speed by 0.3.

Achievement: Unlocked a new item. (Also unlocks the Ball of Bandages) Defeat Mom for the 1st time 6

Item: 208.0 Champion Belt Increases damage, but also increases the chance of champion enemies appearing.

Achievement: Built him out of meat cubes. Make a Super Meat Boy by picking up 4 Cubes of Meat in one run; see methods to create a Super Meat Boy 144

Challenge: Isaac Mom 13.0 Isaac 3 Red Hearts, Blindfolded

Item: 412.0 Cambion Conception After taking damage a certain amount of times, a permanent demonic familiar spawns.

Achievement: Unlocked a new item. Defeat ??? as Lilith 219

Challenge: Isaac Mom 14.0 Isaac 3 Red Hearts